SCHEMBL1768626

SCHEMBL1768626

C=C(C)C(=O)OCCN(CC)CC.C=CN1CCCC1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.36
CHRM1 P11229 4/20 0.36
CHRM3 P20309 3/20 0.36
THRB P10828 1/20 0.35
TSHR P16473 5/20 0.34
CYP3A4 P08684 4/20 0.34
CYP2D6 P10635 4/20 0.34
LMNA P02545 3/20 0.34
CYP1A2 P05177 3/20 0.34
DRD1 P21728 2/20 0.34
DRD3 P35462 2/20 0.34
KCNH2 Q12809 2/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRM1 P35372 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CHRM4 P08173 2/20 0.33
SIGMAR1 Q99720 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4883651 0.90 KMT2A (0.33) THRBTSHRALDH1A1POLBMEN1
SCHEMBL211012 0.88 THRB (0.33) CHRM2CHRM1CHRM3THRBTSHR
SCHEMBL28333248 0.88 THRB (0.41) THRBTSHRLMNAALDH1A1POLB
SCHEMBL11132856 0.87 TSHR (0.41) THRBTSHRLMNAALDH1A1POLB
SCHEMBL3089075 0.86 CHRM2 (0.37) CHRM2CHRM1CHRM3TSHRCYP3A4
SCHEMBL10598332 0.84 TSHR (0.49) THRBTSHRLMNAALDH1A1POLB
Sulfuric Acid SCHEMBL4396939 0.84 THRB (0.31) CHRM2CHRM1CHRM3THRBTSHR
SCHEMBL8358756 0.84 TSHR (0.35) CHRM2CHRM1CHRM3THRBTSHR
SCHEMBL3141829 0.84 THRB (0.36) THRBTSHRLMNAALDH1A1POLB
SCHEMBL19513944 0.84 THRB (0.37) THRBTSHRLMNAALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220218588-A1 METHOD AND SYSTEM FOR REMOVING MAKEUP L'ORÉAL (FR) 2022-07-14 US disclosed
US-8323628-B2 Long wear cosmetic composition L'OREAL (FR) 2012-12-04 US disclosed
US-20110123472-A1 LONG WEAR COSMETIC COMPOSITION L'OREAL S.A. 2011-05-26 US disclosed
US-6827928-B2 Transfer resistance, long wearing, and waterproof properties L'OREAL S.A. (FR) 2004-12-07 US disclosed
EP-1253905-A1 HIGH GLOSS MASCARA L'OREAL (FR) 2002-11-06 EP disclosed
US-20020110573-A1 Cosmetic compositions containing di-block, tri-block, multi-block and radial block copolymers L'OREAL 2002-08-15 US disclosed
US-6423306-B2 TRANSFER RESISTANT COSMETIC COMPRISING AT LEAST ONE RADIAL BLOCK COPOLYMER FILM FORMER; EYELINER; MASCARA; LIPSTICK; LOTION L'OREAL SA (FR) 2002-07-23 US disclosed
EP-1214045-A1 COSMETIC COMPOSITIONS CONTAINING SPECIFIC POLYSACCHARIDE RESINS L'OREAL, S.A. (FR) 2002-06-19 EP disclosed
WO-2001054660-A1 HIGH GLOSS MASCARA L'OREAL (FR) 2001-08-02 WO disclosed
US-20010007654-A1 COSMETIC COMPOSITIONS CONTAINING DI-BLOCK, TRI-BLOCK, MULTI-BLOCK AND RADIAL BLOCK COPOLYMERS L'OREAL S.A. (FR) 2001-07-12 US disclosed
WO-2001017488-A1 COSMETIC COMPOSITIONS CONTAINING SPECIFIC POLYSACCHARIDE RESINS L'OREAL SA (FR) 2001-03-15 WO disclosed