Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17686405 | 0.79 | SMYD2 (0.43) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL5566651 | 0.76 | SMYD2 (0.50) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL5569919 | 0.76 | SMYD2 (0.50) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15879423 | 0.76 | SMYD2 (0.45) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15879422 | 0.76 | SMYD2 (0.45) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15209600 | 0.73 | SMYD2 (0.44) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL15215168 | 0.73 | SMYD2 (0.44) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL599505 | 0.71 | SMYD2 (0.49) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL10172041 | 0.71 | SMYD2 (0.49) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9661721 | 0.71 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160108027-A1 | SUBSTITUTED BENZOXAZOLES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108027-A1 | SUBSTITUTED BENZOXAZOLES | TBXA2R, XDH, CYP4X1 | SMYD2 4843/4885CYP3A4 28/4885HTT 2125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.