Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688734 | 1.00 | PTGS2 (0.33) | PTGS2 | |
| SCHEMBL27449958 | 0.91 | — | — | |
| SCHEMBL10776738 | 0.80 | MEN1 (0.33) | — | |
| SCHEMBL17688646 | 0.75 | HDAC2 (0.35) | — | |
| SCHEMBL17688648 | 0.75 | HDAC2 (0.35) | — | |
| SCHEMBL27449960 | 0.75 | HDAC2 (0.30) | — | |
| SCHEMBL10012291 | 0.70 | — | — | |
| SCHEMBL2363187 | 0.69 | — | — | |
| SCHEMBL10012809 | 0.67 | — | — | |
| SCHEMBL7040560 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | claimed |
| EP-3207036-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | University of Florida Research Foundation (US) | 2017-08-23 | — | — | EP | claimed |
| WO-2016061555-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2016-04-21 | — | — | WO | claimed |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-07-09 | — | — | US | disclosed |
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | University of Florda Research Foundation,Incorporated (US) | 2021-05-20 | — | — | US | disclosed |
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | University of Florda Research Foundation,Incorporated (US) | 2021-05-20 | — | — | US | disclosed |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | disclosed |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2017-08-24 | — | — | US | disclosed |
| EP-3207036-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | University of Florida Research Foundation (US) | 2017-08-23 | — | — | EP | disclosed |
| WO-2016061555-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2016-04-21 | — | — | WO | disclosed |
| WO-2016061555-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2016-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147379-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS, COMBINATIONS AND USES THEREOF | MKI67, TP53, PLK1 | PTGS2 1736/4885 |
| US-12030864-B2 | Small molecule anticancer agents, combinations and uses thereof | MKI67, TP53, PCNA | PTGS2 1400/4885 |
| US-20170240570-A1 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | MKI67, TP53, PCNA | PTGS2 1638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.