Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10310957 | 0.93 | TLR7 (0.38) | TLR7NUDT1KDM4EALDH1A1GLA | |
| SCHEMBL174740 | 0.76 | TLR7 (0.52) | TLR7NUDT1 | |
| SCHEMBL563781 | 0.75 | TLR7 (0.54) | TLR7 | |
| SCHEMBL15436859 | 0.75 | TLR7 (0.36) | TLR7KDM4EALDH1A1GLAGAA | |
| SCHEMBL15443134 | 0.75 | TLR7 (0.45) | TLR7 | |
| SCHEMBL3921296 | 0.74 | TLR7 (0.68) | TLR7NUDT1 | |
| SCHEMBL161256 | 0.74 | TLR7 (0.57) | TLR7NUDT1 | |
| SCHEMBL23421426 | 0.72 | TLR7 (0.43) | TLR7 | |
| SCHEMBL23420171 | 0.71 | TLR7 (0.41) | TLR7 | |
| SCHEMBL3933268 | 0.70 | TLR7 (0.57) | TLR7NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375471-B2 | Adjuvanted formulations of booster vaccines | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2016-06-28 | — | — | US | disclosed |
| US-9315530-B2 | Adsorption of immunopotentiators to insoluble metal salts | NOVARTIS AG (CH) | 2016-04-19 | — | — | US | disclosed |