Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 19/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23421426 | 0.85 | TLR7 (0.43) | TLR7 | |
| SCHEMBL563781 | 0.84 | TLR7 (0.54) | TLR7 | |
| SCHEMBL23421010 | 0.84 | TLR7 (0.52) | TLR7TLR8 | |
| SCHEMBL23422287 | 0.83 | MEN1 (0.41) | TLR7LMNAPKMSMN1; SMN2TLR8 | |
| SCHEMBL23421388 | 0.82 | TLR7 (0.55) | TLR7 | |
| SCHEMBL23420712 | 0.82 | TLR7 (0.55) | TLR7 | |
| SCHEMBL23420431 | 0.82 | AKT1 (0.33) | TLR7TLR8 | |
| SCHEMBL23421870 | 0.76 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL23421458 | 0.75 | AKT1 (0.36) | TLR7TLR8 | |
| SCHEMBL23420646 | 0.74 | CDK1 (0.37) | TLR7LMNAPKMSMN1; SMN2TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210154316-A1 | Immunoconjugates | BOLT BIOTHERAPEUTICS, INC. (US) | 2021-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210154316-A1 | Immunoconjugates | FCGR3B, FCGR2A, FCGR1A | TLR7 105/4885LMNA 4727/4885PKM 4867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.