Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TLR4 | O00206 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302128 | 1.00 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL3337615 | 1.00 | LMNA (0.57) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL23651844 | 0.89 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL17772563 | 0.89 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL24105787 | 0.89 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL23651830 | 0.89 | LMNA (0.48) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL16883909 | 0.88 | LMNA (0.54) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL3336078 | 0.88 | LMNA (0.54) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL3336077 | 0.88 | LMNA (0.54) | LMNAKMT2AALDH1A1POLBCYP3A4 | |
| SCHEMBL2335003 | 0.86 | LMNA (0.44) | LMNAKMT2AALDH1A1POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315532-B2 | Fatty acid carbohydrate hybrid molecules as therapeutic agents and methods thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-04-19 | — | — | US | disclosed |