Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127901 | 0.80 | MAPT (0.59) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL31312869 | 0.80 | MAPT (0.59) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL19221810 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL7031588 | 0.76 | ALDH1A1 (0.89) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6156455 | 0.76 | ALDH1A1 (0.96) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL15358737 | 0.75 | MAPT (0.81) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL10126783 | 0.75 | MAPT (0.65) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL519230 | 0.75 | MAPT (0.69) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6272228 | 0.74 | ALDH1A1 (0.86) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL241271 | 0.74 | ALDH1A1 (0.93) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-B9 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-04-20 | — | — | EP | disclosed |