SCHEMBL17690137

SCHEMBL17690137

CC1(C)c2ccccc2-c2c(N(c3ccccc3)c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)cccc21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 3/20 0.35
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816747 0.96 KDM4E (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25125619 0.96 KDM4E (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL18469201 0.95 PDK2 (0.35) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21141333 0.95 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL25563017 0.94 PDK2 (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL17690138 0.94 PDK2 (0.32) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21239090 0.94 PDK2 (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL24646510 0.94 PDK2 (0.34) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL21924884 0.94 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT
SCHEMBL19530817 0.94 KDM4E (0.33) PDK2KDM4EMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160111644-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111644-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
EP-3010066-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2016-04-20 EP disclosed