SCHEMBL21141333

SCHEMBL21141333

CC1(C)c2ccccc2-c2c(N(c3ccc4c(c3)-c3ccccc3-c3ccccc3-c3ccccc3-4)c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)cccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDK2 Q15119 3/20 0.33
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17854351 0.96 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL25125619 0.96 KDM4E (0.34) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17816747 0.96 KDM4E (0.34) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854398 0.95 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21141347 0.95 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17690137 0.95 PDK2 (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21924884 0.94 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL18468883 0.94 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL19530817 0.94 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL21141136 0.94 PDK2 (0.33) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11512038-B2 Tetraphenylene triarylamine compounds Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-11-29 US disclosed
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS Beijing Summer Sprout Technology Co., Ltd. (CN) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11512038-B2 Tetraphenylene triarylamine compounds OCIAD2, OCIAD1, SLC7A5 KDM4E 4100/4885MEN1 3882/4885LMNA 2682/4885
US-20190185412-A1 TETRAPHENYLENE TRIARYLAMINE COMPOUNDS OCIAD2, OCIAD1, SLC7A5 KDM4E 4100/4885MEN1 3882/4885LMNA 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.