Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EYA2 | O00167 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805954 | 0.90 | ALDH1A1 (0.35) | TDP1TSHR | |
| SCHEMBL2185699 | 0.87 | TDP1 (0.43) | TDP1LMNAEYA2APPACE | |
| SCHEMBL6050658 | 0.78 | — | — | |
| SCHEMBL14123945 | 0.74 | TDP1 (0.39) | TDP1LMNAEYA2APPACE | |
| SCHEMBL23502501 | 0.73 | CA12 (0.35) | TDP1LMNAEYA2APPACE | |
| SCHEMBL20043297 | 0.73 | TDP1 (0.32) | TDP1LMNAEYA2APPACE | |
| SCHEMBL14729807 | 0.73 | PAOX (0.32) | — | |
| SCHEMBL13806341 | 0.73 | ALDH1A1 (0.37) | TDP1ALOX15TSHR | |
| SCHEMBL7400280 | 0.71 | TDP1 (0.40) | TDP1LMNAEYA2APPACE | |
| SCHEMBL4116214 | 0.71 | TDP1 (0.40) | TDP1LMNAEYA2APPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201025-B1 | FUNCTIONAL LIPID CONSTRUCTS | KODE BIOTECH LTD (NZ) | 2016-04-20 | — | — | EP | disclosed |