Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 9/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227970 | 0.90 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL20283415 | 0.90 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL13430929 | 0.89 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL13456982 | 0.83 | POLB (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL12556850 | 0.83 | SERPINE1 (0.42) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL11986812 | 0.83 | POLB (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL20283461 | 0.79 | SERPINE1 (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL3227964 | 0.79 | SERPINE1 (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL11987181 | 0.78 | POLB (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL11986809 | 0.78 | SERPINE1 (0.46) | SERPINE1POLBKDM4ELMNAFUT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461786-B1 | PROTECTIVE COMPOSITIONS FOR DERMAL PAPILLA CELLS | SAMI LABS LTD (IN) | 2016-04-20 | — | — | EP | disclosed |