Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 10/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20283461 | 1.00 | SERPINE1 (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL20283415 | 0.83 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL3227970 | 0.83 | SERPINE1 (0.47) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL13430929 | 0.79 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL17690451 | 0.79 | SERPINE1 (0.44) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL12556850 | 0.77 | SERPINE1 (0.42) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL11986812 | 0.77 | POLB (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL13456982 | 0.77 | POLB (0.49) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL20283460 | 0.72 | SERPINE1 (0.41) | SERPINE1POLBKDM4ELMNAFUT7 | |
| SCHEMBL13739212 | 0.72 | POLB (0.59) | SERPINE1POLBKDM4ELMNAFUT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11903990-B2 | Compositions and methods for treating and removing seborrheic keratoses | STOECKER WILLIAM VAN DOVER (US) | 2024-02-20 | — | — | US | claimed |
| CN-114630650-A | Plant active matter and its anti-pollution effect | 萨米-萨宾莎集团有限公司 | 2022-06-14 | — | — | CN | claimed |
| US-20220133828-A1 | Compositions and Methods for Treating and Removing Seborrheic Keratoses | STOECKER WILLIAM VAN DOVER (US) | 2022-05-05 | — | — | US | claimed |
| WO-2018145105-A1 | COMPOSITIONS AND METHODS FOR TREATING AND REMOVING SEBORRHEIC KERATOSES | STOECKER MD WILLIAM VAN DOVER (US) | 2018-08-09 | — | — | WO | claimed |
| US-20180221426-A1 | Compositions and Methods for Treating and Removing Seborrheic Keratoses | STOECKER WILLIAM VAN DOVER (US) | 2018-08-09 | — | — | US | claimed |
| CN-114630650-B | Plant active substance and anti-pollution effect thereof | 萨米-萨宾莎集团有限公司 | 2024-03-29 | — | — | CN | disclosed |
| EP-3554276-B1 | NOVEL COMPOSITIONS FOR TASTE MASKING | INT FLAVORS & FRAGRANCES INC (US) | 2023-05-10 | — | — | EP | disclosed |
| CN-110049688-B | Novel compositions for taste masking | 国际香料和香精公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-114630650-A | Plant active matter and its anti-pollution effect | 萨米-萨宾莎集团有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114630650-A | Plant active matter and its anti-pollution effect | 萨米-萨宾莎集团有限公司 | 2022-06-14 | — | — | CN | disclosed |
| US-11191291-B2 | Compositions for taste masking | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-11191291-B2 | Compositions for taste masking | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-9376369-B2 | Anti-cholesterolemic compounds and methods of use | CHATTERJEE SUBROTO (US) | 2016-06-28 | — | — | US | disclosed |
| US-20140031304-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CHATTERJEE SUBROTO (US) | 2014-01-30 | — | — | US | disclosed |
| US-8492351-B2 | Anti-cholesterolemic compounds and methods of use | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-07-23 | — | — | US | disclosed |
| WO-2010083537-A2 | OPTIMAL BIOLOGICAL MARKER FOR THE BIOLOGICAL POTENCY OF EMBLICA OFFICINALIS GAERTN. (AMLA) FRUIT-METHODS AND PRODUCTS THEREOF | SAMI LABS LIMITED (IN) | 2010-07-22 | — | — | WO | disclosed |
| US-20100063153-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100062989-A1 | OPTIMAL BIOLOGICAL MARKER FOR THE BIOLOGICAL POTENCY OF Emblica Officinalis Gaertn. (AMLA) FRUIT-METHODS AND PRODUCTS THEREOF | MAJEED MUHAMMED | 2010-03-11 | — | — | US | disclosed |
| EP-2094085-A2 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | The Johns Hopkins University (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008080162-A2 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180221426-A1 | Compositions and Methods for Treating and Removing Seborrheic Keratoses | CAT, CUTA, GPX1 | SERPINE1 120/4885POLB 352/4885KDM4E 2485/4885 |
| US-20220133828-A1 | Compositions and Methods for Treating and Removing Seborrheic Keratoses | CAT, CUTA, GPX1 | SERPINE1 120/4885POLB 352/4885KDM4E 2485/4885 |
| US-20100063153-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CETP, NPC1L1, HMGCR | SERPINE1 1091/4885POLB 2357/4885KDM4E 2327/4885 |
| US-11903990-B2 | Compositions and methods for treating and removing seborrheic keratoses | CAT, CUTA, GPX1 | SERPINE1 120/4885POLB 352/4885KDM4E 2485/4885 |
| US-20140031304-A1 | ANTI-CHOLESTEROLEMIC COMPOUNDS AND METHODS OF USE | CETP, NPC1L1, HMGCR | SERPINE1 1091/4885POLB 2357/4885KDM4E 2327/4885 |
| US-20100062989-A1 | OPTIMAL BIOLOGICAL MARKER FOR THE BIOLOGICAL POTENCY OF Emblica Officinalis Gaertn. (AMLA) FRUIT-METHODS AND PRODUCTS THEREOF | LGALS1, RBP1, BMP1 | SERPINE1 507/4885POLB 4301/4885KDM4E 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.