Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MFN2 | O95140 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13457724 | 1.00 | EPHX2 (0.50) | EPHX2LMNABLMKMT2AARG1 | |
| SCHEMBL17690627 | 1.00 | EPHX2 (0.50) | EPHX2LMNABLMKMT2AARG1 | |
| Hydrochloric Acid SCHEMBL5114605 | 0.90 | LMNA (0.45) | EPHX2LMNABLMKMT2AARG1 | |
| Hydrochloric Acid SCHEMBL29244862 | 0.90 | LMNA (0.45) | EPHX2LMNABLMKMT2AARG1 | |
| SCHEMBL15906222 | 0.84 | EPHX1 (0.46) | LMNABLMKMT2AARG1ARG2 | |
| SCHEMBL15906224 | 0.84 | EPHX1 (0.46) | LMNABLMKMT2AARG1ARG2 | |
| SCHEMBL18459935 | 0.83 | EPHX1 (0.48) | EPHX2LMNABLMKMT2AMMP2 | |
| SCHEMBL18459934 | 0.83 | EPHX1 (0.48) | EPHX2LMNABLMKMT2AMMP2 | |
| Hydrochloric Acid SCHEMBL9718091 | 0.81 | EPHX1 (0.47) | EPHX2LMNABLMKMT2AMMP2 | |
| SCHEMBL14652087 | 0.81 | LMNA (0.42) | LMNABLMKMT2AARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321272-B1 | ORGANIC COMPOUNDS | NABRIVA THERAPEUTICS AG (AT) | 2016-04-20 | — | — | EP | disclosed |