Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770923 | 0.82 | KMT2A (0.39) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL15380801 | 0.82 | KMT2A (0.39) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL771725 | 0.74 | CHRM2 (0.39) | KMT2AMEN1POLBMAPTCHRM2 | |
| SCHEMBL771724 | 0.74 | CHRM2 (0.39) | KMT2AMEN1POLBMAPTCHRM2 | |
| SCHEMBL31542034 | 0.74 | MEN1 (0.71) | KMT2AMEN1POLBMAPTCHRM2 | |
| SCHEMBL770922 | 0.72 | CHRM2 (0.37) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL770513 | 0.72 | KMT2A (0.56) | KMT2AMEN1POLBMAPTCYP1A2 | |
| SCHEMBL8641154 | 0.72 | MEN1 (0.63) | KMT2AMEN1POLBMAPTL3MBTL1 | |
| SCHEMBL12763881 | 0.71 | MEN1 (0.57) | KMT2AMEN1POLBMAPTCHRM2 | |
| SCHEMBL770724 | 0.70 | HSD11B1 (0.40) | KMT2AMEN1POLBMAPTGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |