Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL771464 | 0.91 | DRD2 (0.51) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL17690713 | 0.90 | DRD2 (0.44) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL17690745 | 0.85 | POLB (0.50) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL14229122 | 0.85 | DRD2 (0.47) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL770218 | 0.85 | NPC1 (0.48) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL770615 | 0.84 | DRD2 (0.49) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL770944 | 0.84 | DRD2 (0.49) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL15224209 | 0.83 | DRD2 (0.46) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL794474 | 0.83 | DRD2 (0.48) | DRD2DRD4POLBTDP1NPC1 | |
| SCHEMBL17690765 | 0.82 | MEN1 (0.49) | DRD2DRD4POLBTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |