SCHEMBL17692008

SCHEMBL17692008

c1ccc(-c2ccnc(-c3cc4ccc5ccccc5c4c4ccccc34)n2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
KDM4E B2RXH2 5/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
AURKA O14965 1/20 0.42
HSP90AA1 P07900 1/20 0.42
PRKACA P17612 1/20 0.42
ADORA2A P29274 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
KMT2A Q03164 6/20 0.39
MEN1 O00255 3/20 0.39
PIM1 P11309 2/20 0.39
PIM3 Q86V86 2/20 0.39
PIM2 Q9P1W9 2/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17691992 0.89 KMT2A (0.41) MAPTKDM4EALDH1A1HPGDAURKA
SCHEMBL9976899 0.84 MAPT (0.51) MAPTKDM4EALDH1A1HPGDADORA2A
SCHEMBL17691982 0.82 ALDH1A1 (0.44) MAPTKDM4EALDH1A1HPGDHSP90AA1
SCHEMBL17692026 0.81 KDM4E (0.42) MAPTKDM4EALDH1A1HPGDHSP90AA1
SCHEMBL17692005 0.81 MAPT (0.46) MAPTKDM4EALDH1A1HPGDADORA2A
SCHEMBL12144395 0.80 MAPT (0.44) MAPTKDM4EALDH1A1HPGDADORA2A
SCHEMBL18732404 0.80 MAPT (0.49) MAPTKDM4EALDH1A1HPGDAURKA
SCHEMBL17691990 0.79 KDM4E (0.47) MAPTKDM4EALDH1A1HPGDKMT2A
SCHEMBL19166495 0.79 KDM4E (0.48) MAPTKDM4EALDH1A1HPGDAURKA
SCHEMBL19167141 0.79 MAPT (0.60) MAPTKDM4EALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed