SCHEMBL17692020

SCHEMBL17692020

c1cc(-c2ccc3ncccc3c2)cc(-c2ccc3c(ccc4cc(-c5cccc(-c6ccc7ncccc7c6)c5)c5ccccc5c43)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
DYRK1A Q13627 1/20 0.46
ERN1 O75460 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP11B1 P15538 1/20 0.40
MCL1 Q07820 1/20 0.40
GRM4 Q14833 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
ERBB2 P04626 1/20 0.39
CYP1A2 P05177 1/20 0.39
FYN P06241 1/20 0.39
MAOA P21397 1/20 0.39
ACHE P22303 1/20 0.39
AHR P35869 1/20 0.39
JAK2 O60674 1/20 0.39
JAK1 P23458 1/20 0.39
TYK2 P29597 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20698345 0.91 NPC1 (0.45) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL17691974 0.88 NPC1 (0.58) POLBNPC1RAB9ADYRK1ACYP3A4
SCHEMBL17691969 0.86 NPC1 (0.55) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL22617913 0.85 NPC1 (0.39) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL17691970 0.84 NPC1 (0.40) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL17691872 0.83 NPC1 (0.72) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL22879909 0.82 NPC1 (0.43) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL17692015 0.82 NPC1 (0.45) POLBNPC1RAB9ADYRK1AERN1
SCHEMBL20698131 0.81 NPC1 (0.43) POLBNPC1RAB9AERN1CYP3A4
SCHEMBL17691977 0.81 CYP3A4 (0.58) POLBNPC1RAB9ADYRK1AERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10826000-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-03 US disclosed
US-20190036043-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-31 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed
US-20160111664-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-21 US disclosed