SCHEMBL22879909

SCHEMBL22879909

c1cc(-c2ccc3c(ccc4ccc5nc(-c6ccc7ncccc7c6)oc5c43)c2)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
POLB P06746 1/20 0.43
GRM4 Q14833 1/20 0.41
DYRK1A Q13627 1/20 0.40
JAK2 O60674 1/20 0.39
JAK1 P23458 1/20 0.39
TYK2 P29597 1/20 0.39
JAK3 P52333 1/20 0.39
CYP11B1 P15538 1/20 0.38
UTRN P46939 2/20 0.37
CYP3A4 P08684 1/20 0.36
ATR Q13535 1/20 0.36
MCL1 Q07820 1/20 0.36
ERN1 O75460 1/20 0.36
DHODH Q02127 1/20 0.35
CYP1A1 P04798 2/20 0.35
CYP1B1 Q16678 2/20 0.35
CYP1A2 P05177 1/20 0.35
HSD17B1 P14061 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22879908 0.92 RAB9A (0.43) NPC1RAB9APOLBGRM4DYRK1A
SCHEMBL21662281 0.89 DHODH (0.44) NPC1RAB9ACYP11B1DHODHCYP1A2
SCHEMBL22880307 0.86 ESR1 (0.45) NPC1RAB9APOLBCYP11B1DHODH
SCHEMBL22880409 0.84 DHODH (0.43) NPC1RAB9ACYP3A4DHODHCYP1A1
SCHEMBL22880415 0.83 DHODH (0.43) NPC1RAB9ADHODHCYP1A1CYP1B1
SCHEMBL22880547 0.83 HSD17B10 (0.39) NPC1RAB9ADHODHCYP1A1CYP1B1
SCHEMBL17692020 0.82 POLB (0.54) NPC1RAB9APOLBGRM4DYRK1A
SCHEMBL22880541 0.82 HSD17B10 (0.38) NPC1RAB9ACYP3A4CYP1A1CYP1B1
SCHEMBL22880323 0.82 ESR1 (0.43) NPC1RAB9APOLBCYP11B1CYP3A4
SCHEMBL21662280 0.81 DHODH (0.44) RAB9AATRMCL1DHODHCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11793075-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-10-17 US disclosed
US-11588112-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 US disclosed
US-20220020931-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2022-01-20 US disclosed
US-20210359216-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-18 US disclosed
US-20210328154-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-10-21 US disclosed
US-20210013427-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220020931-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, SOD1, LIMS1 NPC1 3172/4885RAB9A 1382/4885POLB 2464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.