Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288950 | 0.80 | ALDH1A1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL4851556 | 0.80 | PTGS1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL4956090 | 0.80 | PTGS1 (0.52) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL1236211 | 0.78 | ALDH1A1 (0.50) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL1236209 | 0.78 | ALDH1A1 (0.50) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL21296364 | 0.74 | PTGS1 (0.44) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL24015558 | 0.73 | ALDH1A1 (0.45) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 | |
| SCHEMBL22648921 | 0.73 | MAPT (0.45) | PTGS1ALDH1A1MAPTGRIK1SLC1A1 | |
| SCHEMBL10443781 | 0.73 | ALDH1A1 (0.45) | PTGS1ALDH1A1MAPTGRIK1SLC1A1 | |
| Guanidine SCHEMBL27516721 | 0.73 | PTGS1 (0.45) | PTGS1ALDH1A1MAPTSLC7A5GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501412-A1 | SALT FORM OF A MULTI-ARM POLYMER-DRUG CONJUGATE | Nektar Therapeutics (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011063158-A1 | SALT FORM OF A MULTI-ARM POLYMER-DRUG CONJUGATE | NEKTAR THERAPEUTICS (US) | 2011-05-26 | — | — | WO | disclosed |