Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA3 | P07451 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA5A | P35218 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220574 | 0.79 | CA12 (0.39) | CA1CA2CA9CA12CA3 | |
| SCHEMBL14176144 | 0.77 | ATM (0.49) | POLBCA1CA2CYP3A4HSD17B10 | |
| SCHEMBL2817503 | 0.74 | MAOA (0.52) | CA1CA2CA9CA12CA3 | |
| SCHEMBL1769433 | 0.74 | TSHR (0.47) | CA1CA2CYP3A4HSD17B10LMNA | |
| SCHEMBL1769278 | 0.71 | MEN1 (0.41) | CA1CA2CA9CA12CA3 | |
| SCHEMBL28498471 | 0.70 | HTT (0.57) | POLBCA1CA2CA9CA12 | |
| SCHEMBL4792373 | 0.70 | POLB (0.40) | POLBHSD17B10ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL9812380 | 0.69 | HSD17B10 (0.52) | CA1CA2CA9CA12CA3 | |
| SCHEMBL20476006 | 0.69 | TSHR (0.47) | CA1CA2CYP3A4LMNAALDH1A1 | |
| SCHEMBL5371530 | 0.69 | MAPT (0.45) | POLBCYP3A4LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061760-A1 | NOVEL ANTITHROMBOTIC AGENTS | CADILA HEALTHCARE LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |