SCHEMBL17694550

SCHEMBL17694550

CCCCCCCCCCC1(CCCCCCCCCC)c2cc(-c3ccc([Si](c4ccc(-c5ccccc5)s4)(c4ccc(-c5ccccc5)s4)c4ccc(-c5ccccc5)s4)cc3)ccc2-c2ccc(-c3ccc([Si](c4ccc(-c5ccccc5)s4)(c4ccc(-c5ccccc5)s4)c4ccc(-c5ccccc5)s4)cc3)cc21

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 4/20 0.34
▸ MMP9 P14780 4/20 0.34
▸ MAPT P10636 1/20 0.34
▸ PDK2 Q15119 2/20 0.33
▸ MMP8 P22894 2/20 0.32
▸ MMP13 P45452 2/20 0.32
▸ ALOX15 P16050 2/20 0.31
▸ MGLL Q99685 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ NPC1 O15118 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17694560 0.87 — —
SCHEMBL17694552 0.85 RARB (0.36) MAPTKDM4ENPC1ALDH1A1HPGD
SCHEMBL536401 0.82 MMP2 (0.46) MMP2MMP9PDK2MMP8MMP13
SCHEMBL28942264 0.82 MMP2 (0.46) MMP2MMP9PDK2MMP8MMP13
SCHEMBL12222874 0.80 PDK2 (0.35) MMP2MMP9MAPTPDK2MMP8
SCHEMBL17676869 0.80 — —
SCHEMBL17108443 0.79 PDK2 (0.40) MMP2MMP9PDK2MMP8MMP13
SCHEMBL25444664 0.79 PDK2 (0.33) MMP2MMP9PDK2MMP8MMP13
SCHEMBL17118404 0.79 PDK2 (0.38) MMP2MMP9PDK2MMP8MMP13
SCHEMBL10019514 0.78 MMP2 (0.37) MMP2MMP9PDK2MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777026-B2 Branched oligoarylsilanes and method for producing same LUMINESCENT INNOVATION TECHNOLOGIES LLC (RU) 2017-10-03 — — US disclosed
US-20160108065-A1 Branched Oligoarylsilanes and Method for Producing Same LUMINESCENT INNOVATION TECHNOLOGIES LLC (RU) 2016-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160108065-A1 Branched Oligoarylsilanes and Method for Producing Same SIK3, SIK2, SIK1 MMP2 2841/4885MMP9 3211/4885MAPT 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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