Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082875 | 0.81 | TP53 (0.31) | TP53 | |
| Methylamine SCHEMBL8745534 | 0.71 | — | — | |
| Sulfuric Acid SCHEMBL28166070 | 0.69 | TP53 (0.50) | TP53 | |
| Sulfuric Acid SCHEMBL28862993 | 0.69 | TP53 (0.50) | TP53 | |
| SCHEMBL1535002 | 0.68 | — | — | |
| SCHEMBL6766679 | 0.68 | — | — | |
| Sulfuric Acid SCHEMBL5883810 | 0.67 | TP53 (0.46) | TP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL609217 | 0.67 | TP53 (0.34) | TP53 | |
| SCHEMBL475492 | 0.67 | S1PR2 (0.47) | TP53 | |
| SCHEMBL28982366 | 0.67 | CA5A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2501412-A1 | SALT FORM OF A MULTI-ARM POLYMER-DRUG CONJUGATE | Nektar Therapeutics (US) | 2012-09-26 | — | — | EP | disclosed |
| WO-2011063158-A1 | SALT FORM OF A MULTI-ARM POLYMER-DRUG CONJUGATE | NEKTAR THERAPEUTICS (US) | 2011-05-26 | — | — | WO | disclosed |