Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21415804 | 1.00 | RORC (0.58) | RORC | |
| SCHEMBL17695909 | 1.00 | RORC (0.58) | RORC | |
| SCHEMBL17695961 | 0.91 | RORC (0.56) | RORC | |
| SCHEMBL21415918 | 0.91 | RORC (0.56) | RORC | |
| SCHEMBL21415767 | 0.89 | RORC (0.65) | RORC | |
| SCHEMBL17695826 | 0.89 | RORC (0.65) | RORC | |
| SCHEMBL23343580 | 0.88 | RORC (0.49) | RORC | |
| SCHEMBL21415754 | 0.84 | RORC (0.42) | RORC | |
| SCHEMBL20468693 | 0.84 | RORC (0.72) | RORC | |
| SCHEMBL21415856 | 0.83 | RORC (0.56) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016061160-A1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, INC. (US) | 2016-04-21 | — | — | WO | disclosed |