SCHEMBL1769597

SCHEMBL1769597

O=C(O)N1CCSC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31061811 0.85
SCHEMBL337228 0.83
Hydrochloric Acid SCHEMBL720506 0.81 FAAH (0.42)
SCHEMBL27757963 0.81 DPP7 (0.47)
Benzaldehyde SCHEMBL10665813 0.78 DPP4 (0.46)
Bicarbonate SCHEMBL2561130 0.78 DPP4 (0.43)
SCHEMBL7770099 0.77
SCHEMBL3629899 0.77
SCHEMBL14818004 0.77
SCHEMBL1811646 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926619-B2 Certain pladienolide compounds and methods of use EISAI R & D MANAGEMENT CO., LTD. (JP) 2024-03-12 US claimed
US-20210163456-A1 CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2021-06-03 US claimed
EP-3774759-A2 PLADIENOLIDE COMPOUNDS AND THEIR USE Eisai R&D Management Co., Ltd. (JP) 2021-02-17 EP claimed
WO-2019199667-A2 CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE KEANEY GREGG F (US) 2019-10-17 WO claimed
CN-104530415-B A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance 厦门赛诺邦格生物科技股份有限公司 2017-09-01 CN claimed
EP-1805153-A1 SILANE ESTERS AND AMIDES OF 2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID AND USE THEREOF FOR PREVENTING PHOTOAGEING OF THE SKIN L'Oréal (FR) 2007-07-11 EP claimed
WO-2006045639-A1 SILANE ESTERS AND AMIDES OF 2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID, AND COSMETIC USES THEREOF L'OREAL (FR) 2006-05-04 WO claimed
US-5576154-A X-RAY RECORDING MATERIAL OF SILVER HALIDE EMULSION LAYERS ON SUPPORTS STERLING DIAGNOSTIC IMAGING, INC. (US) 1996-11-19 US claimed
CN-122055379-A Compounds containing one or more diboronate esters and related insulin analogues 普罗托莫科技公司 2026-05-15 CN disclosed
EP-4321504-B1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF XIAMEN SINOPEG BIOTECH CO LTD (CN) 2026-02-18 EP disclosed
US-20250333400-A1 CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-30 US disclosed
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
CN-119465117-A Application of thiazole thioketone compound in electroless copper plating and electroless copper plating solution 广东东硕科技有限公司 2025-02-18 CN disclosed
US-20240368140-A1 CERTAIN PLADIENOLIDE COMPOUNDS AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-11-07 US disclosed
US-5576154-A X-RAY RECORDING MATERIAL OF SILVER HALIDE EMULSION LAYERS ON SUPPORTS STERLING DIAGNOSTIC IMAGING, INC. (US) 1996-11-19 US disclosed
CN-1116823-A Therapeutic uses and delivery systems for dehydroepiandrosterone ENDORECHERCHE INC (CA) 1996-02-14 CN disclosed
CN-1056105-A The peptide that bradykinin-antagonistic action is arranged HOECHST AG (DE) 1991-11-13 CN disclosed
EP-0348541-A1 N-carbethoxy-4-thiazolidine-carboxylic acid, process for its preparation and its use as medicament YASON S.r.l (IT) 1990-01-03 EP disclosed
US-4874776-A N-CARBETHOXY-4-THIAZOLIDINECARBOXYLIC ACID AND SALTS YASON S.R.L. (IT) 1989-10-17 US disclosed
US-4590167-A CHROMATOGRAPHIC PLATE COATED WITH SILICA GEL IMPREGNATED WITH TRANSITION METAL COMPOUND AND CHIRAL SEPARATOR DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-05-20 US disclosed