Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18680527 | 0.91 | MEN1 (0.65) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL12410862 | 0.87 | MEN1 (0.64) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL18680528 | 0.85 | MEN1 (0.62) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL17695457 | 0.85 | MEN1 (0.66) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL15488854 | 0.84 | MEN1 (0.57) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL13932807 | 0.81 | MEN1 (0.64) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL14901855 | 0.79 | MEN1 (0.64) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL11964677 | 0.79 | MEN1 (0.64) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL14046504 | 0.78 | MEN1 (0.77) | MEN1KMT2ABLMUSP2POLB | |
| SCHEMBL12176171 | 0.78 | MEN1 (0.62) | MEN1KMT2ABLMUSP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016061555-A2 | NOVEL SMALL MOLECULE ANTICANCER AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2016-04-21 | — | — | WO | disclosed |