SCHEMBL12410862

SCHEMBL12410862

CCN(CC)c1ccc2c(-c3ccccc3)c3ccc(=[N+](CC)CC)cc-3oc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.64
▸ KMT2A Q03164 5/20 0.64
▸ BLM P54132 2/20 0.64
▸ THRB P10828 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ TDP1 Q9NUW8 1/20 0.64
▸ POLB P06746 3/20 0.63
▸ USP2 O75604 2/20 0.63
▸ PPARG P37231 1/20 0.63
▸ RXFP1 Q9HBX9 1/20 0.63
▸ NCOR2 Q9Y618 1/20 0.63
▸ FPR2 P25090 4/20 0.48
▸ TGM2 P21980 1/20 0.46
▸ ATM Q13315 2/20 0.43
▸ PLEC Q15149 1/20 0.43
▸ AVPR2 P30518 2/20 0.42
▸ CHRM1 P11229 1/20 0.41
▸ TLR7 Q9NYK1 1/20 0.41
▸ ALDH1A1 P00352 3/20 0.40
▸ HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18680527 0.93 MEN1 (0.65) MEN1KMT2ABLMTHRBRECQL
SCHEMBL14046504 0.91 MEN1 (0.77) MEN1KMT2ABLMTHRBRECQL
SCHEMBL14901855 0.87 MEN1 (0.64) MEN1KMT2ABLMTHRBRECQL
SCHEMBL17696488 0.87 MEN1 (0.61) MEN1KMT2ABLMTHRBRECQL
SCHEMBL12176171 0.86 MEN1 (0.62) MEN1KMT2ABLMTHRBRECQL
SCHEMBL20288679 0.86 MEN1 (0.65) MEN1KMT2ABLMTHRBRECQL
SCHEMBL15488854 0.86 MEN1 (0.57) MEN1KMT2ABLMTHRBRECQL
SCHEMBL18680528 0.86 MEN1 (0.62) MEN1KMT2ABLMTHRBRECQL
SCHEMBL13932807 0.86 MEN1 (0.64) MEN1KMT2ABLMTHRBRECQL
SCHEMBL15459413 0.85 MEN1 (0.64) MEN1KMT2ABLMTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220412963-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION 2022-12-29 — — US disclosed
US-11353461-B2 Methods of enhancing MS detection of tagged glycans WATERS TECHNOLOGIES CORPORATION (US) 2022-06-07 — — US disclosed
US-11061023-B2 Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2021-07-13 — — US disclosed
US-20190331669-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2019-10-31 — — US disclosed
US-20190219587-A1 METHODS OF ENHANCING MS DETECTION OF TAGGED GLYCANS WATERS TECHNOLOGIES CORPORATION 2019-07-18 — — US disclosed
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 — — US disclosed
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION (US) 2016-05-19 — — US disclosed
US-20140219925-A1 POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2014-08-07 — — US disclosed
US-20110166297-A1 MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) Sailo Nanotechnologies Ltd. (IL) 2011-07-07 — — US disclosed
US-20080199811-A1 PHOTOSENSITIVE COMPOSITION AND TWO-PHOTON ABSORPTION PHOTORECORDING MEDIUM FUJIFILM CORPORATION (JP) 2008-08-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190331669-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS FUT5, FUT6, OGT MEN1 3289/4885KMT2A 2258/4885BLM 4084/4885
US-20220412963-A1 FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS FUT5, FUT6, OGT MEN1 3289/4885KMT2A 2258/4885BLM 4084/4885
US-20140219925-A1 POLYMER PARTICLES OR NANO-VECTORS AND USE THEREOF AS A DRUG AND/OR DIAGNOSTIC AGENT ABCB1, TSG101, CD44 MEN1 1305/4885KMT2A 4340/4885BLM 2010/4885
US-20160139136-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS FUT5, FUT6, CSGALNACT1 MEN1 2746/4885KMT2A 3081/4885BLM 3624/4885
US-11061023-B2 Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals FUT5, FUT6, OGT MEN1 3289/4885KMT2A 2258/4885BLM 4084/4885
US-20110166297-A1 MOLECULARLY IMPRINTED SMART POLYMERS (MISPs) MSI2, SLIRP, BRAP MEN1 470/4885KMT2A 1647/4885BLM 784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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