Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 10/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063361 | 0.77 | MAPK1 (0.49) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL23294884 | 0.76 | MAPK1 (0.44) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL30832576 | 0.74 | MAPK1 (0.41) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL30832579 | 0.74 | MAPK1 (0.41) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL30832575 | 0.74 | MAPK1 (0.41) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL210247 | 0.72 | MAPK1 (0.61) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL4570717 | 0.72 | MAPK1 (0.61) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL9010746 | 0.72 | MAPK1 (0.61) | MAPK1TSHRKDM4EHTTTDP1 | |
| SCHEMBL823093 | 0.72 | ALOX12 (0.43) | MAPK1TSHRKDM4EHTTTDP1 | |
| Alpha-Pinene SCHEMBL338721 | 0.71 | MAPK1 (0.92) | MAPK1TSHRKDM4EHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113302266-B | Traction fluid | 路博润公司 | 2023-02-24 | — | — | CN | disclosed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD. (AU) | 2014-03-06 | — | — | US | disclosed |
| US-8592399-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2013-11-26 | — | — | US | disclosed |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| US-20100273683-A1 | Compositions having hase rheology modifiers | SPECIALTY OPERATIONS FRANCE (FR) | 2010-10-28 | — | — | US | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | MAPK1 2166/4885TSHR 354/4885KDM4E 1508/4885 |
| US-20100273683-A1 | Compositions having hase rheology modifiers | WEE2, CCNE2, HPSE | MAPK1 2981/4885TSHR 4655/4885KDM4E 1293/4885 |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR5, S1PR2 | MAPK1 2166/4885TSHR 354/4885KDM4E 1508/4885 |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR2, S1PR5 | MAPK1 2408/4885TSHR 262/4885KDM4E 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.