SCHEMBL17697907

SCHEMBL17697907

COc1cc2c(N)nc(N3CCN(C(=O)CC4CCN4)CC3)nc2c(F)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CFD P00746 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16689386 1.00 CFD (1.00) CFD
SCHEMBL16681215 0.94 CFD (1.00) CFD
SCHEMBL16681212 0.94 CFD (1.00) CFD
SCHEMBL16680562 0.93 CFD (1.00) CFD
SCHEMBL16680559 0.93 CFD (1.00) CFD
SCHEMBL20956553 0.87 CFD (0.78) CFD
Hydrochloric Acid SCHEMBL20956513 0.87 CFD (0.77) CFD
Hydrochloric Acid SCHEMBL29562756 0.87 CFD (0.77) CFD
SCHEMBL17697977 0.87 CFD (1.00) CFD
SCHEMBL16689393 0.87 CFD (1.00) CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9452990-B2 Complement pathway modulators and uses thereof NOVARTIS AG (CH) 2016-09-27 US claimed
EP-2864322-B1 COMPLEMENT PATHWAY MODULATORS AND USES THEREOF NOVARTIS AG (CH) 2016-04-27 EP claimed