SCHEMBL17698449

SCHEMBL17698449

Oc1[c]ccc2c(Cl)cccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.54
CYP2A6 P11509 3/20 0.54
NR4A2 P43354 1/20 0.43
ADRA2A P08913 1/20 0.37
TSHR P16473 2/20 0.37
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 2/20 0.33
DAO P14920 2/20 0.33
ATM Q13315 1/20 0.33
KDM4E B2RXH2 3/20 0.32
MAPT P10636 2/20 0.32
LMNA P02545 2/20 0.32
BRD4 O60885 1/20 0.32
HSP90AA1 P07900 1/20 0.32
METAP2 P50579 1/20 0.32
METAP1 P53582 1/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2145668 0.79
SCHEMBL5031421 0.78 IDO1 (0.46) CYP1A2TSHRALDH1A1KMT2AKDM4E
SCHEMBL6847193 0.75 ALDH1A1 (0.54) NR4A2TSHRALDH1A1KMT2AKDM4E
SCHEMBL16586070 0.75 CYP1A2 (0.54) CYP1A2CYP2A6NR4A2ADRA2ATSHR
SCHEMBL11606547 0.74 CYP1A2 (0.46) CYP1A2CYP2A6NR4A2TSHRALDH1A1
SCHEMBL2468811 0.74 CYP1A2 (1.00) CYP1A2CYP2A6NR4A2ADRA2ATSHR
SCHEMBL29629127 0.74 CYP1A2 (1.00) CYP1A2CYP2A6NR4A2ADRA2ATSHR
SCHEMBL9621428 0.72 CYP1A2 (0.33) CYP1A2CYP2A6TSHRMAPTHSD17B10
SCHEMBL29212679 0.71 MEN1 (0.44) CYP1A2CYP2A6TSHRALDH1A1KMT2A
SCHEMBL29094148 0.71 CYP1A2 (0.48) CYP1A2CYP2A6NR4A2ADRA2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115605464-B Novel compound and organic light emitting device comprising the same 株式会社LG化学 2024-04-09 CN disclosed
CN-117546629-A Organic light emitting device 株式会社LG化学 2024-02-09 CN disclosed
EP-2262500-B1 THIENOPYRIDONE DERIVATIVES AS AMP-ACTIVATED PROTEIN KINASE (AMPK) ACTIVATORS MERCK PATENT GMBH (DE) 2016-04-27 EP disclosed