Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355021 | 0.94 | HSD11B1 (0.36) | HSD11B1SLC34A1P2RX7MAPTABCB11 | |
| SCHEMBL171531 | 0.94 | HSD11B1 (0.36) | HSD11B1SLC34A1P2RX7MAPTABCB11 | |
| SCHEMBL29368758 | 0.94 | HSD11B1 (0.39) | HSD11B1SLC34A1IGF1RCXCR2P2RX7 | |
| SCHEMBL173254 | 0.94 | HSD11B1 (0.39) | HSD11B1SLC34A1IGF1RCXCR2P2RX7 | |
| SCHEMBL29369400 | 0.91 | HSD11B1 (0.43) | HSD11B1SLC34A1IGF1RP2RX7MAPT | |
| SCHEMBL29367616 | 0.91 | MAPT (0.35) | SLC34A1CXCR2MAPTKDM4EGALR3 | |
| SCHEMBL14956153 | 0.91 | MAPT (0.35) | SLC34A1CXCR2MAPTKDM4EGALR3 | |
| SCHEMBL170786 | 0.91 | HSD11B1 (0.43) | HSD11B1SLC34A1IGF1RP2RX7MAPT | |
| SCHEMBL15155523 | 0.87 | MAPT (0.36) | SLC34A1MAPTKDM4EGALR3HTT | |
| SCHEMBL29367611 | 0.87 | HSD11B1 (0.42) | HSD11B1SLC34A1IGF1RP2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3011832-A1 | FUNGICIDAL COMBINATION COMPRISING PHENOXYPHENYLAMIDINES AND FURTHER FUNGICIDE | Bayer CropScience AG (DE) | 2016-04-27 | — | — | EP | disclosed |