Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045463 | 0.85 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL2843513 | 0.81 | HSD11B1 (0.65) | HSD11B1HSD11B2 | |
| SCHEMBL5935247 | 0.81 | HSD11B1 (0.65) | HSD11B1HSD11B2 | |
| SCHEMBL5935277 | 0.78 | HSD11B1 (0.61) | HSD11B1HSD11B2 | |
| SCHEMBL5935278 | 0.78 | HSD11B1 (0.61) | HSD11B1HSD11B2 | |
| SCHEMBL1042152 | 0.74 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL2829375 | 0.74 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL2829377 | 0.74 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL1044046 | 0.72 | HSD11B1 (0.70) | HSD11B1HSD11B2 | |
| SCHEMBL1046268 | 0.72 | HSD11B1 (0.70) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269977-B1 | Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme | ABBVIE INC (US) | 2016-04-27 | — | — | EP | disclosed |