Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17701617 | 0.94 | P2RX3 (0.53) | P2RX3 | |
| SCHEMBL17701614 | 0.94 | P2RX3 (0.58) | P2RX3 | |
| SCHEMBL16310007 | 0.94 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL16310006 | 0.92 | P2RX3 (0.68) | P2RX3 | |
| SCHEMBL17701613 | 0.92 | P2RX3 (0.55) | P2RX3 | |
| SCHEMBL16309932 | 0.88 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL17689804 | 0.88 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL16309809 | 0.87 | P2RX3 (0.52) | P2RX3 | |
| SCHEMBL17701680 | 0.87 | P2RX3 (0.63) | P2RX3 | |
| SCHEMBL16309812 | 0.87 | P2RX3 (0.63) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732060-B2 | Aminotriazine derivative and pharmaceutical composition comprising the same | SHIONOGI & CO., LTD. (JP) | 2017-08-15 | — | — | US | disclosed |
| US-20160115151-A1 | AMINOTRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | SHIONOGI & CO., LTD. (JP) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160115151-A1 | AMINOTRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | P2RX3, P2RX2, P2RX1 | P2RX3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.