Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CMKLR1 | Q99788 | 3/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237767 | 0.89 | HTR3A (0.46) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL176753 | 0.86 | CYP4F2 (0.44) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL176886 | 0.85 | FFAR1 (0.43) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL3339869 | 0.85 | CYP4F2 (0.41) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL176881 | 0.84 | CYP4F2 (0.44) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL177618 | 0.84 | KDM4E (0.43) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL2237687 | 0.84 | KDM4E (0.43) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL2303237 | 0.84 | HTR3A (0.44) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL177024 | 0.83 | CYP4F2 (0.43) | HTR3ACYP4F2CYP4A11CNR1CNR2 | |
| SCHEMBL12348081 | 0.81 | HTR3A (0.41) | HTR3ACYP4F2CYP4A11CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |