SCHEMBL17703183

SCHEMBL17703183

COCCO[Si](OCCO)(OCCO)OCCOC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49921 0.86
SCHEMBL987278 0.83 TSHR (0.44) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL18162038 0.81
SCHEMBL16977915 0.80
SCHEMBL663290 0.78 CA2 (0.35)
SCHEMBL170484 0.78 TSHR (0.35) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL2198981 0.78 CA2 (0.35)
2-Methoxyethanol SCHEMBL1224960 0.76 TSHR (0.44) ALDH1A1TSHRMAPK1MEN1KMT2A
SCHEMBL19961850 0.76
SCHEMBL16151445 0.76 TSHR (0.40) ALDH1A1TSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9403949-B2 Acetoacetyl-functional silicon-based resin and process for preparing the same VALSPAR SOURCING, INC. (US) 2016-08-02 US disclosed
US-20160115279-A1 ACETOACETYL-FUNCTIONAL SILICON-BASED RESIN AND PROCESS FOR PREPARING THE SAME SWIMC LLC 2016-04-28 US disclosed