SCHEMBL17705459

SCHEMBL17705459

c1ccc2c(-n3c4ccccc4c4oc5ccccc5c43)cccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
TDP1 Q9NUW8 2/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
POLB P06746 2/20 0.36
GSR P00390 1/20 0.35
HSD17B10 Q99714 2/20 0.35
NPC1 O15118 1/20 0.35
MAPK1 P28482 1/20 0.35
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2D6 P10635 1/20 0.35
NCF1 P14598 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
HTR1D P28221 1/20 0.35
HTR1B P28222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245996 0.90 CNR1 (0.38) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL15128462 0.88 GSR (0.38) CNR1CNR2TDP1POLBGSR
SCHEMBL17705474 0.86 ALOX5 (0.38) POLBHSD17B10NPC1MAPK1ALDH1A1
SCHEMBL17246194 0.84 CNR1 (0.38) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL17246030 0.83 CNR1 (0.34) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL17690859 0.83 TDP1 (0.41) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL17451676 0.81 CNR1 (0.37) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL17246196 0.81 TDP1 (0.42) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL19986022 0.81 CNR1 (0.37) CNR1CNR2TDP1GSK3AGSK3B
SCHEMBL17246192 0.81 CNR1 (0.37) CNR1CNR2TDP1GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed