SCHEMBL17705481

SCHEMBL17705481

c1ccc2c(c1)oc1c(-c3ccc(-n4c5ccccc5c5oc6ccccc6c54)cc3)cccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
PRKDC P78527 5/20 0.39
GGPS1 O95749 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
ATM Q13315 2/20 0.35
PTGES2 Q9H7Z7 1/20 0.35
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
PPARG P37231 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15759597 0.94 ALOX5 (0.48) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17690925 0.92 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15759609 0.92 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL12286339 0.90 ALOX5 (0.49) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15678671 0.89 ALOX5 (0.54) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL24173847 0.88 ALOX5 (0.52) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL21388925 0.88 ALOX5 (0.52) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17358411 0.88 ALOX5 (0.52) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL14208828 0.87 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17734282 0.87 ALOX5 (0.50) ALOX5PRKDCGGPS1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-9818950-B2 Organic light-emitting devices SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-14 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed
US-20160118590-A1 ORGANIC LIGHT-EMITTING DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2016-04-28 US disclosed