Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.57 |
| ▸ | F10 | P00742 | 6/20 | 0.57 |
| ▸ | PLG | P00747 | 3/20 | 0.57 |
| ▸ | F9 | P00740 | 2/20 | 0.57 |
| ▸ | PLAT | P00750 | 2/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771006 | 0.93 | F2 (0.60) | F2F10PLGF9PLAT | |
| SCHEMBL3407590 | 0.90 | F2 (0.69) | F2F10PLGF9PLAT | |
| SCHEMBL12096057 | 0.90 | F2 (0.60) | F2F10PLGF9PLAT | |
| SCHEMBL12096144 | 0.90 | F2 (0.52) | F2F10PLGF9PLAT | |
| Hydrochloric Acid SCHEMBL3401700 | 0.89 | F2 (0.69) | F2F10PLGF9PLAT | |
| SCHEMBL1770238 | 0.89 | F2 (0.57) | F2F10PLGF9PLAT | |
| SCHEMBL3404410 | 0.89 | F2 (0.58) | F2F10PLGF9PLAT | |
| SCHEMBL12095996 | 0.89 | F2 (0.56) | F2F10PLGF9PLAT | |
| SCHEMBL12095828 | 0.89 | F2 (0.58) | F2F10PLGF9PLAT | |
| SCHEMBL12096013 | 0.89 | F2 (0.58) | F2F10PLGF9PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254881-B1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI SA (FR) | 2012-09-12 | — | — | EP | disclosed |
| US-20110112075-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | SANOFI-AVENTIS (FR) | 2011-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110112075-A1 | CHLOROTHIOPHENE-AMIDES AS INHIBITORS OF COAGULATION FACTORS XA AND THROMBIN | F12, F3, F2 | F2 3/4885F10 6/4885PLG 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.