SCHEMBL17707142

SCHEMBL17707142

CCO[Si](CCCCCOCCNCCOCCCCC[Si](OCC)(OCC)OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17707216 1.00 KDM4E (0.33) KDM4ERECQLMEN1THRBHTT
SCHEMBL17706962 0.98 KDM4E (0.33) KDM4ERECQLTSHR
SCHEMBL28828249 0.93 CYP2C19 (0.31) MEN1KMT2ATSHR
SCHEMBL17706861 0.92 KDM4E (0.34) KDM4ERECQLTSHR
SCHEMBL28065675 0.87 EPHX1 (0.30)
SCHEMBL28065614 0.85 CYP2C19 (0.33) MEN1HTTKMT2ATSHR
SCHEMBL29117965 0.84 TSHR (0.43) KDM4ERECQLMEN1THRBHTT
SCHEMBL31165551 0.84 TSHR (0.43) KDM4ERECQLMEN1THRBHTT
SCHEMBL28560547 0.84 TSHR (0.43) KDM4ERECQLMEN1THRBHTT
SCHEMBL28554749 0.84 TSHR (0.43) KDM4ERECQLMEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3015471-B1 NOVEL BISALKOXYSILANE COMPOUND AND ITS PRODUCTION METHOD SHINETSU CHEMICAL CO (JP) 2018-02-28 EP disclosed
EP-3015471-A1 NOVEL BISALKOXYSILANE COMPOUND AND ITS PRODUCTION METHOD Shin-Etsu Chemical Co., Ltd. (JP) 2016-05-04 EP disclosed