SCHEMBL28065614

SCHEMBL28065614

CCNCCOCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28828249 0.93 CYP2C19 (0.31) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL17706861 0.92 KDM4E (0.34) CYP2C19CYP1A2TSHR
SCHEMBL17706962 0.87 KDM4E (0.33) TSHR
SCHEMBL17707216 0.85 KDM4E (0.33) MEN1KMT2ATSHRHTT
SCHEMBL17707142 0.85 KDM4E (0.33) MEN1KMT2ATSHRHTT
SCHEMBL3503366 0.84 TSHR (0.33) MEN1KMT2ATSHRHTT
SCHEMBL8752858 0.83
SCHEMBL270457 0.82 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2ACYP1A2
SCHEMBL17991841 0.82 TSHR (0.32) TSHR
SCHEMBL15705449 0.82 MEN1 (0.33) MEN1KMT2ATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105566373-A Novel bisalkoxysilane compound and its production method SHINETSU CHEMICAL CO 2016-05-11 CN disclosed