SCHEMBL17711596

SCHEMBL17711596

c1ccc(C(OC(c2ccccc2)(c2ccccc2)[C@@H]2CO2)(c2ccccc2)[C@@H]2CO2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 3/20 0.33
LMNA P02545 2/20 0.33
CYP2D6 P10635 2/20 0.33
HRH1 P35367 1/20 0.33
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KCNN4 O15554 1/20 0.32
ALOX15 P16050 1/20 0.31
SLC6A2 P23975 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7161862 1.00 TSHR (0.38) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL10773125 0.88 MEN1 (0.41) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL28474936 0.80 CYP2C9 (0.30) TSHRMEN1KMT2AALOX15CYP2C19
SCHEMBL692302 0.77 MEN1 (0.49) TSHRMEN1KMT2ATDP1ALDH1A1
SCHEMBL10613864 0.77 TSHR (0.37) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL3474878 0.75 MEN1 (0.42) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL133959 0.75 TSHR (0.39) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL8068587 0.75 CYP2D6 (0.39) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL30825821 0.75 TSHR (0.42) TSHRMEN1KMT2ATDP1MAPK1
SCHEMBL30825836 0.75 TSHR (0.42) TSHRMEN1KMT2ATDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160121576-A1 ELECTROCONDUCTIVE PRESSURE-SENSITIVE ADHESIVE CUSHIONING NITTO DENKO CORPORATION (JP) 2016-05-05 US disclosed