SCHEMBL3474878

SCHEMBL3474878

CC(OC(C)(c1ccccc1)C1CO1)(c1ccccc1)C1CO1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 3/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP2B6 P20813 1/20 0.33
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
CYP1A2 P05177 1/20 0.33
PPARG P37231 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 2/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
CHRM3 P20309 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20261897 0.86 KMT2A (0.41) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL1665727 0.77 MEN1 (0.41) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL10773125 0.77 MEN1 (0.41) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL28629123 0.76 MEN1 (0.43) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL10958748 0.75 TSHR (0.35) MEN1KMT2AALDH1A1TSHRTP53
SCHEMBL7161862 0.75 TSHR (0.38) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL14003863 0.75 MAPK1 (0.42) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL17711596 0.75 TSHR (0.38) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL10613864 0.73 TSHR (0.37) MEN1KMT2AMAPK1ALDH1A1ALOX15
SCHEMBL8677979 0.72 CHRM2 (0.34) MEN1KMT2ACHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104450641-B A kind of epoxide hydrolase and its encoding gene and application 华东理工大学 2018-03-06 CN claimed
CN-104450641-A Epoxide hydrolase as well as encoding gene and application thereof UNIV EAST CHINA SCIENCE & TECH 2015-03-25 CN claimed
CN-105566878-B High-fire resistance polymerized thylene carbonate hydrocarbon ester resin composition SK新技术株式会社 2019-07-19 CN disclosed
CN-109609479-A A kind of Aspergillus usamii epoxide hydrolase mutant that enantioselectivity improves 江南大学 2019-04-12 CN disclosed
CN-108885920-A Resin composition 三菱化学株式会社 2018-11-23 CN disclosed
CN-104302701-B With the polyalkylene carbonate resin combination for interpenetrating type cross-linked structure SK新技术株式会社 2018-10-26 CN disclosed
EP-2013261-B1 STABILIZERS FOR IMPROVED OPEN TIME OF AQUEOUS COATINGS HERCULES LLC (US) 2018-10-24 EP disclosed
CN-104450641-B A kind of epoxide hydrolase and its encoding gene and application 华东理工大学 2018-03-06 CN disclosed
US-9828508-B2 Rapid cure polysulfide coatings for cavitation resistance, erosion resistance, and sound damping THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2017-11-28 US disclosed
CN-107189970-A A kind of cloudy city pseudomonad YC1612 and its application and preparation method for producing halide alcohol dehalogenase 盐城工学院 2017-09-22 CN disclosed
US-20160312063-A1 Rapid Cure Polysulfide Coatings for Cavitation Resistance, Erosion Resistance, and Sound Damping THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2016-10-27 US disclosed
US-20090253832-A1 COLORANT COMPATIBLE HYDROPHOBICALLY MODIFIED POLYURETHANE THICKENER FOR PAINT AVOCA LLC 2009-10-08 US disclosed
US-7550542-B2 Colorant compatible synthetic thickener for paint HERCULES INCORPORATED (US) 2009-06-23 US disclosed
EP-2013261-A2 STABILIZERS FOR IMPROVED OPEN TIME OF AQUEOUS COATINGS Hercules Incorporated (US) 2009-01-14 EP disclosed
EP-1709126-B1 COLORANT COMPATIBLE SYNTHETIC THICKENER FOR PAINT HERCULES INC (US) 2008-03-12 EP disclosed
WO-2007124142-A2 STABILIZERS FOR IMPROVED OPEN TIME OF AQUEOUS COATINGS HERCULES INCORPORATED (US) 2007-11-01 WO disclosed
US-20070249780-A1 Stabilizers for improved open time of aqueous coatings BAKEEV KIRILL 2007-10-25 US disclosed
EP-1709126-A1 COLORANT COMPATIBLE SYNTHETIC THICKENER FOR PAINT Hercules Incorporated (US) 2006-10-11 EP disclosed
WO-2005068564-A1 COLORANT COMPATIBLE SYNTHETIC THICKENER FOR PAINT HERCULES INCORPORATED (US) 2005-07-28 WO disclosed
US-20050150418-A1 Colorant compatible synthetic thickener for paint PHARMACHEM LABORATORIES LLC 2005-07-14 US disclosed