Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714572 | 1.00 | CA2 (0.55) | CA2MAPK1FFAR1FFAR4PPARG | |
| SCHEMBL2175685 | 0.98 | CA2 (0.57) | CA2MAPK1FFAR1FFAR4PPARG | |
| SCHEMBL2175684 | 0.98 | CA2 (0.57) | CA2MAPK1FFAR1FFAR4PPARG | |
| Hydrochloric Acid SCHEMBL30192502 | 0.96 | CA2 (0.55) | CA2MAPK1FFAR1FFAR4PPARG | |
| SCHEMBL8332015 | 0.93 | CA2 (0.59) | CA2MAPK1TERTMAPTBLM | |
| SCHEMBL8332014 | 0.93 | CA2 (0.59) | CA2MAPK1TERTMAPTBLM | |
| SCHEMBL9782158 | 0.88 | PPARG (0.53) | FFAR1FFAR4PPARGTERTPTPN1 | |
| SCHEMBL11572750 | 0.86 | PPARG (0.61) | FFAR1FFAR4PPARGTERTPTPN1 | |
| SCHEMBL11572092 | 0.86 | PPARG (0.61) | FFAR1FFAR4PPARGTERTPTPN1 | |
| SCHEMBL29034443 | 0.86 | GRIK1 (0.50) | FFAR1FFAR4PPARGTERTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016065602-A1 | INHIBITORS OF RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2016-05-06 | — | — | WO | disclosed |