Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9922660 | 0.84 | P2RY12 (0.42) | TDP1GAACD274PDCD1MEN1 | |
| SCHEMBL9922422 | 0.77 | P2RY12 (0.47) | CD274PDCD1MEN1MAPTKMT2A | |
| SCHEMBL12161734 | 0.76 | P2RY12 (0.44) | TDP1CD274PDCD1MEN1MAPT | |
| SCHEMBL9922661 | 0.74 | P2RY12 (0.44) | TDP1GAACD274PDCD1MEN1 | |
| SCHEMBL9922662 | 0.69 | P2RY12 (0.44) | TDP1GAACD274PDCD1MEN1 | |
| SCHEMBL9922659 | 0.68 | MAPT (0.42) | TDP1GAACD274PDCD1MEN1 | |
| SCHEMBL9922228 | 0.68 | FBP1 (0.42) | TDP1GAACD274PDCD1MEN1 | |
| SCHEMBL9922416 | 0.68 | P2RY12 (0.48) | MEN1MAPTKMT2APOLBHTT | |
| SCHEMBL9922229 | 0.67 | FBP1 (0.46) | TDP1CD274PDCD1MEN1MAPT | |
| SCHEMBL12161733 | 0.67 | P2RY12 (0.46) | MEN1MAPTKMT2APOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314593-B1 | PLATELET ADP RECEPTOR INHIBITORS | PORTOLA PHARM INC (US) | 2016-05-04 | — | — | EP | disclosed |