Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238106 | 0.90 | L3MBTL1 (0.53) | SLC22A12S1PR3 | |
| SCHEMBL176885 | 0.74 | SLC22A12 (0.52) | SLC22A12S1PR3PLA2G2AALDH1A1TDP1 | |
| SCHEMBL26137617 | 0.73 | SLC22A12 (0.50) | SLC22A12MEN1KMT2ATDP1PDE5A | |
| SCHEMBL2305598 | 0.72 | L3MBTL1 (0.49) | SLC22A12MEN1KMT2AKLKB1 | |
| SCHEMBL13777322 | 0.71 | CNR1 (0.54) | SLC22A12ALDH1A1HPGDMAPK1PDE5A | |
| SCHEMBL21649244 | 0.70 | SLC22A12 (0.47) | SLC22A12TDP1PDE5A | |
| SCHEMBL3128916 | 0.70 | PTGS1 (0.46) | ALDH1A1HPGDKLKB1 | |
| SCHEMBL2240917 | 0.69 | SCN8A (0.50) | KMT2A | |
| SCHEMBL23832442 | 0.69 | PPARG (0.60) | ALDH1A1HPGDMAPK1MEN1KMT2A | |
| SCHEMBL1967017 | 0.68 | CPT1A (0.48) | ALDH1A1HPGDPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345644-A1 | INDAZOLE COMPOUND | Asahi Kasei Pharma Corporation (JP) | 2011-07-20 | — | — | EP | disclosed |