SCHEMBL17719176

SCHEMBL17719176

O=C(O)c1ccc2nc(-c3cccnc3)c(CN3CCOCC3)n2c1

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 19/20 0.75
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ KDM4E B2RXH2 1/20 0.52
▸ HTT P42858 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718904 0.86 SLC2A1 (1.00) SLC2A1SMN1; SMN2
SCHEMBL17718905 0.83 SLC2A1 (0.77) SLC2A1KDM4EHTT
SCHEMBL17719177 0.81 SLC2A1 (0.73) SLC2A1SMN1; SMN2KDM4EHTT
SCHEMBL17718857 0.79 SLC2A1 (1.00) SLC2A1KDM4EHTT
SCHEMBL2361512 0.78 SLC2A1 (0.53) SLC2A1SMN1; SMN2KDM4EHTT
SCHEMBL17718879 0.77 SLC2A1 (0.84) SLC2A1SMN1; SMN2
SCHEMBL17718873 0.75 SLC2A1 (1.00) SLC2A1SMN1; SMN2KDM4EHTT
SCHEMBL17718848 0.75 SLC2A1 (0.89) SLC2A1SMN1; SMN2
SCHEMBL17718882 0.73 SLC2A1 (0.73) SLC2A1SMN1; SMN2
SCHEMBL12819486 0.72 SLC2A1 (0.63) SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS IOMET PHARMA LTD. (GB) 2016-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160120863-A1 SLC2A TRANSPORTER INHIBITORS SLCO1A2, SLCO2B1, SLCO2A1 SLC2A1 6/4885SMN1; SMN2 3724/4885KDM4E 4043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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