Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 19/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17718905 | 0.78 | SLC2A1 (0.77) | SLC2A1KDM4EHTT | |
| SCHEMBL17719176 | 0.78 | SLC2A1 (0.75) | SLC2A1SMN1; SMN2KDM4EHTT | |
| SCHEMBL29668411 | 0.74 | POLB (0.45) | SLC2A1KDM4EHTT | |
| SCHEMBL17718884 | 0.71 | SLC2A1 (0.73) | SLC2A1SMN1; SMN2 | |
| SCHEMBL17718882 | 0.71 | SLC2A1 (0.73) | SLC2A1SMN1; SMN2 | |
| SCHEMBL17722629 | 0.70 | SLC2A1 (1.00) | SLC2A1KDM4EHTT | |
| SCHEMBL17718933 | 0.70 | SLC2A1 (1.00) | SLC2A1KDM4EHTT | |
| SCHEMBL17718889 | 0.70 | SLC2A1 (1.00) | SLC2A1KDM4EHTT | |
| SCHEMBL17718872 | 0.69 | SLC2A1 (0.65) | SLC2A1SMN1; SMN2 | |
| SCHEMBL17718913 | 0.68 | SLC2A1 (0.64) | SLC2A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536706-A1 | ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | Celgene Corporation (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011100380-A1 | ARYLMETHOXY ISOINDOLINE DERIVATIVES AND COMPOSITIONS COMPRISING AND METHODS OF USING THE SAME | CELGENE CORPORATION (US) | 2011-08-18 | — | — | WO | disclosed |