⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26273792 | 1.00 | — | — | |
| SCHEMBL18371662 | 0.87 | TNK2 (0.35) | — | |
| SCHEMBL10120675 | 0.87 | TNK2 (0.35) | — | |
| SCHEMBL10120838 | 0.87 | TNK2 (0.35) | — | |
| SCHEMBL17719386 | 0.87 | TNK2 (0.35) | — | |
| SCHEMBL17719358 | 0.85 | — | — | |
| SCHEMBL17719234 | 0.85 | — | — | |
| SCHEMBL19223088 | 0.82 | PTPN1 (0.36) | — | |
| SCHEMBL19412421 | 0.81 | TSHR (0.32) | — | |
| SCHEMBL17131343 | 0.81 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239830-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD. (CN) | 2024-07-18 | — | — | US | disclosed |
| US-20230295214-A1 | METHODS OF PREPARING 1`-CYANO NUCLEOSIDES | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-9724360-B2 | Methods for treating Filoviridae virus infections | GILEAD SCIENCES, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20160122374-A1 | METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2016-05-05 | — | — | US | disclosed |