⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17719234 | 1.00 | — | — | |
| SCHEMBL17719232 | 0.88 | TMPRSS2 (0.35) | — | |
| SCHEMBL17719370 | 0.88 | TMPRSS2 (0.35) | — | |
| SCHEMBL18623842 | 0.88 | TMPRSS2 (0.35) | — | |
| SCHEMBL10120684 | 0.88 | TMPRSS2 (0.35) | — | |
| SCHEMBL17719233 | 0.85 | — | — | |
| SCHEMBL26273792 | 0.85 | — | — | |
| SCHEMBL10120843 | 0.79 | RIPK1 (0.31) | — | |
| SCHEMBL17719377 | 0.79 | RIPK1 (0.31) | — | |
| SCHEMBL25821865 | 0.77 | TNK2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295214-A1 | METHODS OF PREPARING 1`-CYANO NUCLEOSIDES | GILEAD SCIENCES, INC. | 2023-09-21 | — | — | US | disclosed |
| US-20160122356-A1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES, INC. | 2016-05-05 | — | — | US | disclosed |