Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843058 | 0.87 | CYP1A2 (0.48) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL12668290 | 0.85 | STAT3 (0.46) | STAT3STAT1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL12057410 | 0.85 | STAT3 (0.47) | STAT3STAT1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL585139 | 0.84 | STAT3 (0.41) | STAT3STAT1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL1854874 | 0.84 | STAT3 (0.55) | STAT3STAT1TERTPPARGPPARA | |
| SCHEMBL585272 | 0.84 | STAT3 (0.55) | STAT3STAT1PPARGPPARADHFR | |
| SCHEMBL585041 | 0.83 | STAT3 (0.46) | STAT3STAT1GCGR | |
| SCHEMBL12057412 | 0.83 | STAT3 (0.46) | STAT3STAT1PPARGPPARATSHR | |
| SCHEMBL1861760 | 0.83 | STAT3 (0.52) | STAT3STAT1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL588717 | 0.83 | STAT3 (0.41) | STAT3STAT1CYP1A2CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9326511-B2 | Methods of inhibiting microbial biofilms | DESTINY PHARMA LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |