Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 8/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585272 | 0.89 | STAT3 (0.55) | STAT3STAT1HDAC6HDAC3HDAC4 | |
| SCHEMBL12449775 | 0.87 | STAT3 (0.45) | STAT3STAT1PDE2APDE3BPDE3A | |
| SCHEMBL1861760 | 0.86 | STAT3 (0.52) | STAT3STAT1CHEK2 | |
| SCHEMBL584793 | 0.86 | STAT3 (0.52) | STAT3STAT1HDAC6HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL29883333 | 0.85 | STAT3 (0.51) | STAT3STAT1AURKAHDAC6HDAC3 | |
| Hydrochloric Acid SCHEMBL584374 | 0.85 | STAT3 (0.51) | STAT3STAT1AURKAHDAC6HDAC3 | |
| SCHEMBL1856477 | 0.85 | STAT3 (0.50) | STAT3STAT1HDAC6HDAC3HDAC4 | |
| SCHEMBL12057410 | 0.84 | STAT3 (0.47) | STAT3STAT1AURKAHDAC6HDAC3 | |
| SCHEMBL4745594 | 0.84 | STAT3 (0.52) | STAT3STAT1AURKAHDAC6HDAC3 | |
| SCHEMBL12633119 | 0.84 | STAT3 (0.49) | STAT3STAT1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | claimed |
| JP-4751068-B2 | — | — | 2011-08-17 | — | — | JP | claimed |
| EP-1558616-B1 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2008-02-27 | — | — | EP | claimed |
| US-20060040914-A1 | Meso-substituted porphyrins | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2006-02-23 | — | — | US | claimed |
| EP-1558616-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI (IT) | 2005-08-03 | — | — | EP | claimed |
| WO-2004035590-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A (IT) | 2004-04-29 | — | — | WO | claimed |
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| US-8288528-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A. (IT) | 2012-10-16 | — | — | US | disclosed |
| EP-1558616-B2 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2011-08-24 | — | — | EP | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-7947674-B2 | Meso-substituted porphyrins | L. Molteni & C. Dei Fratelli Alitti (IT) | 2011-05-24 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |
| US-20110112464-A1 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2011-05-12 | — | — | US | disclosed |
| EP-1558616-B1 | MESO-SUBSTITUTED PORPHYRINS | MOLTENI & C (IT) | 2008-02-27 | — | — | EP | disclosed |
| US-20060040914-A1 | Meso-substituted porphyrins | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A. (IT) | 2006-02-23 | — | — | US | disclosed |
| EP-1558616-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO SOCIETA' PER AZIONI (IT) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035590-A2 | MESO-SUBSTITUTED PORPHYRINS | L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A (IT) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040914-A1 | Meso-substituted porphyrins | PPOX, PPIF, ALAD | STAT3 4208/4885STAT1 3609/4885PDE2A 3245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.